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PhID contains six different types of entities: drugs(chemicals), target(proteins), diseases, genes, side-effects, and pathways, which integreted from 14 public resources (list below).The results of entities retrieved and mapping from theses databases are summarized in Table-1.xls.
PhID provides visualize the comlex relationships among diseases, targets, drugs, genes, side-effects and pathways. Users can search the database using the entities names or common database indentifiers like Drugbank, HMDB, Uniprot, OMIM, HGNC, SIDER and SMPDB. It also provides two tools to predict drug-target interactions.
Qian-Nan Hu, Zhe Deng, Weizhong Tu, Xiaoyan Yang, Zhibin Meng, Zixin Deng and Juan Liu. VNP: Interactive Visual Network Pharmacology of Diseases, Targets and Drugs. CPT: Pharmacometrics & Systems Pharmacology, 2014, 3, e105. Pubmed Link: 24622768
Dong-Sheng Cao,Yi-Zeng Liang,Zhe Deng,Qian-Nan Hu,Min He,Qing-Song Xu,Guang-Hua Zhou,Liu-Xia Zhang,Zi-xin Deng,Shao Liu. Genome-Scale Screening of Drug-Target Associations Relevant to Ki Using a Chemogenomics Approach. PLoS One. 2013;8(4):e57680 Pubmed Link: 23577055
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Entities:
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| Drugs (Chemicals): | 332263 |
| Targets (Proteins): | 24059 |
| Diseases: | 8530 |
| Genes | 43415 |
| Side-effects: | 4492 |
| Pathways: | 867 |
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